Siglec-3/CD33, Human (HEK293)
HY-P73643
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameSiglec-3/CD33, Human (HEK293)
- Delivery Days Customer10
- CertificationResearch Use Only
- Gene ID945
- Target nameCD33
- Target descriptionCD33 molecule
- Target synonymsCD33rSiglec, SIGLEC-3, SIGLEC3, p67, myeloid cell surface antigen CD33, CD33 antigen (gp67), CD33 molecule transcript, gp67, sialic acid-binding Ig-like lectin 3
- Scientific DescriptionSiglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Human (HEK293) is the recombinant human-derived Siglec-3/CD33 protein, expressed by HEK293 , with tag free.
- UNSPSC41116100
- SpeciesHuman