Siglec-3/CD33, Mouse (G236R, HEK293, His)

MedChem Express

Siglec-3/CD33, Mouse (G236R, HEK293, His)

10

Research Use Only

98.0

Cd33

CD33 molecule

Siglec-3, gp67, myeloid cell surface antigen CD33, CD33 antigen, sialic acid-binding Ig-like lectin 3

Myeloid cell surface antigen CD33

Siglec-3/CD33, a sialic-acid-binding lectin, crucially mediates cell-cell interactions and immune cell quiescence. Preferring sialic acid on specific mucins, it forms homodimers, interacting with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation. CD33 also engages C1QA through its C-terminus, activating CD33 inhibitory motifs. Siglec-3/CD33 Protein, Mouse (G236R, HEK293, His) is the recombinant mouse-derived Siglec-3/CD33 protein, expressed by HEK293 , with C-6*His labeled tag.

-20°C

41116100

Mouse