Siglec-5 antibody [1A5]

GeneTex

Siglec-5 antibody [1A5]

9

This antibody reacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

1A5

1 mg/ml

Unconjugated

SIGLEC5

sialic acid binding Ig like lectin 5

CD170; CD33 antigen-like 2; CD33L2; OB-binding protein 2; OBBP2; OB-BP2; obesity-binding protein 2; sialic acid-binding Ig-like lectin 5; sialic acid-binding immunoglobulin-like lectin 5; SIGLEC-5

Mouse

IgG1

Sialic acid-binding Ig-like lectin 5

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]

Human, Primate

2°C to 8°C

12352203