
WB analysis of Molt-4 cell lysate using GTX88527 SIGLEC8 antibody, Internal. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
SIGLEC8 antibody, Internal
GTX88527
Overview
- SupplierGeneTex
- Product NameSIGLEC8 antibody, Internal
- Delivery Days Customer7
- Application Supplier NoteWB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID27181
- Target nameSIGLEC8
- Target descriptionsialic acid binding Ig like lectin 8
- Target synonymsCDw329; SAF2; SAF-2; sialic acid-binding Ig-like lectin 8; sialoadhesin family member 2; SIGLEC-8; SIGLEC8L
- HostGoat
- IsotypeIgG
- Protein IDQ9NYZ4
- Protein NameSialic acid-binding Ig-like lectin 8
- Scientific DescriptionSialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203