Bio-Connect

Siguazodan [115344-47-3]

HY-19026
MedChem Express
CAS Number115344-47-3
Product group Chemicals
Estimated Purity99.0
Molecular Weight284.323
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Siguazodan [115344-47-3]
  • Delivery Days Customer
    10
  • CAS Number
    115344-47-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C14H16N6O
  • Molecular Weight
    284.323
  • Scientific Description
    Siguazodan (SKF 94836) is a potent, selective and orally active phosphodiesterase III (PDE-III) inhibitor with an IC50 of 117 nM. Siguazodan increases cAMP accumulation in intact platelets with an EC50 of 18.88 microM. Siguazodan also inhibits phenylephrine-induced 5-HT release with an IC50 value of 4.2 microM[1][2][3].
  • SMILES
    O=C1CC(C)C(C2=CC=C(/N=C(NC)/NC#N)C=C2)=NN1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200