Silver sulfadiazine [22199-08-2]

MedChem Express

Silver sulfadiazine [22199-08-2]

9

22199-08-2

Research Use Only

98.0

C10H9AgN4O2S

357.14

Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication[1].

NC(C=C1)=CC=C1S2(=O[Ag+][N]3=CC=C[N-]C3=N2)=O

2°C to 8°C

12352200