Silychristin [33889-69-9]

MedChem Express

Silychristin [33889-69-9]

10

33889-69-9

Research Use Only

99.91

C25H22O10

482.44

Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[1][2].

O=C1[C@H](O)[C@@H](C2=CC(O)=C(O[C@@H](C3=CC=C(O)C(OC)=C3)[C@@H]4CO)C4=C2)OC5=CC(O)=CC(O)=C15

-20°C,2°C to 8°C

12352200