Bio-Connect

SIMR3030 [2708270-99-7]

HY-149940
MedChem Express
CAS Number2708270-99-7
Product group Chemicals
Molecular Weight427.54
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SIMR3030 [2708270-99-7]
  • Delivery Days Customer
    10
  • CAS Number
    2708270-99-7
  • Certification
    Research Use Only
  • Molecular Formula
    C27H29N3O2
  • Molecular Weight
    427.54
  • Scientific Description
    SIMR3030 is a potent SARS-CoV-2 PLpro inhibitor with an IC50 value of 0.0399 microg/mL. SIMR3030 shows antiviral activity. SIMR3030 decreases SARS-CoV spike, ORF1b, IFN-alpha, IL-6 mRNA expression. SIMR3030 exhibits a satisfactory safety profile in mice[1].
  • SMILES
    [H][C@@]12CC[C@]3(CC4=C(NC5=C4C=C(C=C5)OC)C[C@]3(N1CCC6=C2NC7=CC=CC=C76)[H])OC
  • UNSPSC
    12131703