Simufilam

MedChem Express

Simufilam [1224591-33-6]

10

1224591-33-6

Research Use Only

98.08

C15H21N3O

259.35

Simufilam (PTI-125) is an orally active FLNA modulator. Simufilam restores NMDAR signaling and Arc expression. Simufilam inhibits overactive mTOR signaling by restoring the normal conformation of FLNA, improves insulin sensitivity, reduces Abeta42-induced neuroinflammation and tau protein hyperphosphorylation. Simufilam can be used for research of Alzheimers disease[1][2][3].

O=C1N(CC2=CC=CC=C2)C3(CCN(C)CC3)NC1

-20°C,2°C to 8°C

12352200