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Simvastatin acid [121009-77-6]

HY-119695
MedChem Express
CAS Number121009-77-6
Product group Chemicals
Estimated Purity95.51
Molecular Weight436.58
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Simvastatin acid [121009-77-6]
  • Delivery Days Customer
    10
  • CAS Number
    121009-77-6
  • Certification
    Research Use Only
  • Estimated Purity
    95.51
  • Molecular Formula
    C25H40O6
  • Molecular Weight
    436.58
  • Scientific Description
    Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin (HY-17502), is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].
  • SMILES
    O=C(C[C@@H](C[C@@H](CC[C@H]1[C@H](C=CC2=C[C@@H](C[C@@H]([C@]12[H])OC(C(C)(CC)C)=O)C)C)O)O)O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200