Simvastatin acid (calcium hydrate) [530112-57-3]

MedChem Express

Simvastatin acid (calcium hydrate) [530112-57-3]

5

530112-57-3

Research Use Only

C25H40O6.1/2Ca.xH2O

Simvastatin acid (Tenivastatin) calcium hydrate is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid calcium hydrate reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid calcium hydrate can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].

CCC(C)(C)C(O[C@@H]1[C@@]2([H])C(C=C[C@@H]([C@@H]2CC[C@@H](O)C[C@@H](O)CC(O)=O)C)=C[C@@H](C1)C)=O.[1/2Ca].[xH2O]

12352200