Simvastatin sodium

Biorbyt

Simvastatin sodium [101314-97-0]

10

101314-97-0

Research Use Only

C25H40NAO6

459.5712795

Simvastatin sodium is a lactone prodrug, can be hydrolysed to active hydroxy-acid by non-specific carboxyesterases or non-enzymatic processes. Simvastatin sodium shows a inhibition of HMG-CoA reductase with a Ki value of 0.12 nM.

CCC(C)(C)C(O[C@@H]1C2[C@H]([C@@H](C)C=CC2=C[C@H](C)C1)CCC(O)C[C@@H](O)CC([O-])=O)=O.[NaH]

12352200