Bio-Connect

SIN1 Antibody

Research Use Only
ORB248120
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    SIN1 Antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    Western blot: 1-3ug/ml WB
  • Certification
    Research Use Only
  • Isotype
    IgG
  • Scientific Description
    mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
  • UNSPSC
    12352203