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Siramesine hydrochloride

M2593
AbMole BioScience
CAS Number224177-60-0
DownloadDatasheet
Product group Chemicals
Estimated Purity>99.0%
Molecular Weight491.04
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Siramesine hydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    224177-60-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99.0%
  • Molecular Formula
    C30H32ClFN2O
  • Molecular Weight
    491.04
  • Scientific Description
    Siramesine (Lu 28-179) hydrochloride is an effective sigma-2 receptor agonist. Siramesine has a nanomolar affinity for sigma-2 receptors (IC50=0.12 nM) and is 140 times more selective for sigma-2 receptors (IC50=17 nM). Siramesine has xC-system inhibitory activity associated with iron death.
  • SMILES
    Cl.FC1=CC=C(C=C1)[N]2C=C(CCCCN3CCC4(CC3)OCC5=C4C=CC=C5)C6=C2C=CC=C6
  • UNSPSC
    12352200