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Staining of mouse peritoneal macrophages using SIRP antibody (GTX29295) and purified mouse IgG2a isotype control.
Staining of mouse peritoneal macrophages using SIRP antibody (GTX29295) and purified mouse IgG2a isotype control.
Staining of mouse peritoneal macrophages using SIRP antibody (GTX29295) and purified mouse IgG2a isotype control.

SIRP alpha antibody [MRC OX-41]

GTX29295
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityMouse, Rat
TargetSirpa
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Overview

  • Supplier
    GeneTex
  • Product Name
    SIRP alpha antibody [MRC OX-41]
  • Delivery Days Customer
    9
  • Application Supplier Note
    Flow Cytometry: 1:100Immunohistochemistry (frozen): 1:20 - 1:100Immunohistochemistry (paraffin): 1:20 - 1:100Flow cytometry: Use 10microl of the suggested working dilution to label 10^6 cells. Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MRC OX-41
  • Concentration
    8 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID25528
  • Target name
    Sirpa
  • Target description
    signal-regulatory protein alpha
  • Target synonyms
    Bit, Ptpns1, SHPS-1, tyrosine-protein phosphatase non-receptor type substrate 1, Brain immunoglobulin like protein with tyrosine - based activation motifs, CD172 antigen-like family member A, Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1), SHP substrate 1, brain Ig-like molecule with tyrosine-based activation motifs, inhibitory receptor SHPS-1, macrophage fusion receptor, macrophage membrane protein MFP150, signal-regulatory protein alpha-1, sirp-alpha-1
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP97710
  • Protein Name
    Tyrosine-protein phosphatase non-receptor type substrate 1
  • Scientific Description
    plays a role in macrophage fusion [RGD, Feb 2006]
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lacotte S, Oldani G, Slits F, et al. Alloimmune activation promotes anti-cancer cytotoxicity after rat liver transplantation. PLoS One. 2014,9(3):e91515. doi: 10.1371/journal.pone.0091515
    Read this paper