Sirt1/2-IN-1 [2402779-21-7]
HY-146013
CAS Number2402779-21-7
Product group Chemicals
Molecular Weight420.93
Overview
- SupplierMedChem Express
- Product NameSirt1/2-IN-1 [2402779-21-7]
- Delivery Days Customer10
- CAS Number2402779-21-7
- CertificationResearch Use Only
- Molecular FormulaC22H13ClN2OS2
- Molecular Weight420.93
- Scientific DescriptionSirt1/2-IN-1 (Compound 7) is a SIRT1 and SIRT2 inhibitor with IC50 values of 1.81, 2.10 and 20.5 microg/mL against SIRT1, SIRT2 and SIRT3, respectively. Sirt1/2-IN-1 displays activity in hyperacetylation of alpha-tubulin protein with an IC50 of 32.05 microg/mL. Sirt1/2-IN-1 shows prominent anticancer activity[1].
- SMILESO=C1CSC2=NC(C3=CC(Cl)=CC=C3S4)=C4C(C5=CC=C6C=CC=CC6=C5)N21
- UNSPSC12131703