SIRT1/2/3-IN-2 [388086-13-3]
HY-114906
CAS Number388086-13-3
Product group Chemicals
Molecular Weight397.25
Overview
- SupplierMedChem Express
- Product NameSIRT1/2/3-IN-2 [388086-13-3]
- Delivery Days Customer5
- CAS Number388086-13-3
- CertificationResearch Use Only
- Molecular FormulaC21H14Cl2N2O2
- Molecular Weight397.25
- Scientific DescriptionSIRT1/2/3-IN-2 (compound 9) is a potent SIRT inhibitor, with inhibition rates of 27%, 72%, and 71% targeting SIRT1, SIRT2, and SIRT3, respectively, at 200 microM. SIRT3 is a potential tumor suppressor or promoter, and its increased transcription may be associated with lymph node-positive breast cancer and oral squamous cell carcinoma[1].
- SMILESClC1=C(C2=NC3=CC(NC(CC4=CC=CC=C4)=O)=CC=C3O2)C=CC(Cl)=C1
- UNSPSC12352200