SIRT2-IN-11 [1005095-06-6]
HY-148408
CAS Number1005095-06-6
Product group Chemicals
Estimated Purity99.94
Molecular Weight318.41
Overview
- SupplierMedChem Express
- Product NameSIRT2-IN-11 [1005095-06-6]
- Delivery Days Customer10
- CAS Number1005095-06-6
- CertificationResearch Use Only
- Estimated Purity99.94
- Molecular FormulaC21H22N2O
- Molecular Weight318.41
- Scientific DescriptionSIRT2-IN-11 (AEM1) is a selective SIRT2 inhibitor with an IC50 value of 18.5 microM. SIRT2-IN-11 p53-dependently induces apoptosis, activates expression of CDKN1A, PUMA and NOXA, and increases acetylation of p53. SIRT2-IN-11 can be used for the research of p53-related cancers[1].
- SMILESO=C(C1=CC=C2NC(C3C(C4CCC3C4)C2=C1)C5=CC=CC=C5)N
- Storage Instruction2°C to 8°C
- UNSPSC12131703