SIRT3 antibody [C3], C-term
GTX106292
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSIRT3
Overview
- SupplierGeneTex
- Product NameSIRT3 antibody [C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.7 mg/ml
- ConjugateUnconjugated
- Gene ID23410
- Target nameSIRT3
- Target descriptionsirtuin 3
- Target synonymsSIR2L3, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, NAD-dependent deacetylase sirtuin-3, mitochondrial, NAD-dependent protein delactylase sirtuin-3, SIR2-like protein 3, mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase, regulatory protein SIR2 homolog 3, silent mating type information regulation 2, S.cerevisiae, homolog 3, sir2-like 3, sirtuin type 3
- HostRabbit
- IsotypeIgG
- Protein IDQ9NTG7
- Protein NameNAD-dependent protein deacetylase sirtuin-3, mitochondrial
- Scientific DescriptionThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chen IC, Chiang WF, Chen PF, et al. STRESS-responsive deacetylase SIRT3 is up-regulated by areca nut extract-induced oxidative stress in human oral keratinocytes. J Cell Biochem. 2014,115(2):328-39. doi: 10.1002/jcb.24667Read this paper





