SIRT6-IN-2 [891002-11-2]
HY-103721
CAS Number891002-11-2
Product group Chemicals
Estimated Purity99.85
Molecular Weight366.32
Overview
- SupplierMedChem Express
- Product NameSIRT6-IN-2 [891002-11-2]
- Delivery Days Customer14
- CAS Number891002-11-2
- CertificationResearch Use Only
- Estimated Purity99.85
- Molecular FormulaC19H14N2O6
- Molecular Weight366.32
- Scientific DescriptionSIRT6-IN-2 (Compound 5) is a selective SIRT6 inhibitor (IC50: 34 microM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects[1].
- SMILESO=C(C1=CC=C(NC(C2=CC=CO2)=O)C=C1)NC3=CC(C(O)=O)=C(O)C=C3
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200