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SIS3

HY-13013
MedChem Express
CAS Number521984-48-5
DownloadMSDS
Product group Chemicals
Estimated Purity98.71
Molecular Weight489.99
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SIS3 [521984-48-5]
  • Delivery Days Customer
    10
  • CAS Number
    521984-48-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.71
  • Molecular Formula
    C28H28ClN3O3
  • Molecular Weight
    489.99
  • Scientific Description
    (E)-SIS3 is a potent and selective inhibitor of Smad3 with an IC 50 of 3 microM for Smad3 phosphorylation. (E)-SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-beta1 [1] .
  • SMILES
    [H]Cl.O=C(/C=C/C1=C(N(C2=NC=CC=C21)C)C3=CC=CC=C3)N4CC5=C(CC4)C=C(C(OC)=C5)OC
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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