SIS3

MedChem Express

SIS3 [521984-48-5]

10

521984-48-5

Research Use Only

98.71

C28H28ClN3O3

489.99

(E)-SIS3 is a potent and selective inhibitor of Smad3 with an IC 50 of 3 microM for Smad3 phosphorylation. (E)-SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-beta1 [1] .

[H]Cl.O=C(/C=C/C1=C(N(C2=NC=CC=C21)C)C3=CC=CC=C3)N4CC5=C(CC4)C=C(C(OC)=C5)OC

2°C to 8°C

12352200