Sivelestat [127373-66-4]

MedChem Express

Sivelestat [127373-66-4]

10

127373-66-4

Research Use Only

99.34

C20H22N2O7S

434.46

Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19[1][2][3][4].

CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O)=O)=O)=O)C=C1)=O

2°C to 8°C

12352200