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SK1-I [1072443-89-0]

HY-119016
MedChem Express
CAS Number1072443-89-0
Product group Chemicals
Estimated Purity98.83
Molecular Weight277.40
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SK1-I [1072443-89-0]
  • Delivery Days Customer
    10
  • CAS Number
    1072443-89-0
  • Certification
    Research Use Only
  • Estimated Purity
    98.83
  • Molecular Formula
    C17H27NO2
  • Molecular Weight
    277.40
  • Scientific Description
    SK1-I (BML-258), an analog of sphingosine, is an isozyme-specific competitive SPHK1 inhibitor with a Ki value of 10 microM[1]. SK1-I shows no activity at SPHK1 PKCalpha, PKCdelta, PKA, AKT1, ERK1, EGFR, CDK2, IKKbeta or CamK2beta. SK1-I enhances autophagy and has antitumor activity[2].
  • SMILES
    OC[C@H]([C@H](/C=C/C1=CC=C(C=C1)CCCCC)O)NC
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200