SKF 83959 (hydrobromide)

MedChem Express

SKF 83959 (hydrobromide) [67287-95-0]

10

67287-95-0

Research Use Only

99.86

C18H21BrClNO2

398.72

SKF83959 hydrobromide is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 hydrobromide K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 hydrobromide is a potent allosteric modulator of sigma (sigma)-1 receptor. SKF83959 hydrobromide belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 hydrobromide can be used for the research of Alzheimers disease and depression [1] [2] [3] [4] .

OC1=C(O)C=C2C(C3=CC=CC(C)=C3)CN(C)CCC2=C1Cl.[H]Br

-20°C

12352200