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SKF-96365 hydrochloride Chemical Structure
SKF-96365 hydrochloride Chemical Structure
SKF-96365 hydrochloride Chemical Structure

SKF-96365 (hydrochloride)

HY-100001
MedChem Express
CAS Number130495-35-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.71
Molecular Weight402.91
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SKF-96365 (hydrochloride) [130495-35-1]
  • Delivery Days Customer
    10
  • CAS Number
    130495-35-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.71
  • Molecular Formula
    C22H27ClN2O3
  • Molecular Weight
    402.91
  • Scientific Description
    SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca 2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells [1] [2] .
  • SMILES
    COC1=CC=C(CCCOC(C2=CC=C(OC)C=C2)CN3C=CN=C3)C=C1.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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SKF-96365FFA49535
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