
SKF-96365 hydrochloride Chemical Structure
SKF-96365 (hydrochloride) [130495-35-1]
HY-100001
CAS Number130495-35-1
Product group Chemicals
Estimated Purity99.71
Molecular Weight402.91
Overview
- SupplierMedChem Express
- Product NameSKF-96365 (hydrochloride) [130495-35-1]
- Delivery Days Customer10
- CAS Number130495-35-1
- CertificationResearch Use Only
- Estimated Purity99.71
- Molecular FormulaC22H27ClN2O3
- Molecular Weight402.91
- Scientific DescriptionSKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells[1][2].
- SMILESCOC1=CC=C(CCCOC(C2=CC=C(OC)C=C2)CN3C=CN=C3)C=C1.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
![SKF-96365 hydrochloride [130495-35-1]](https://www.targetmol.com/group3/M00/37/FB/CgoaEWayVMSESgp9AAAAAGX9CZ4900.png)