SKI-I [306301-68-8]

MedChem Express

SKI-I [306301-68-8]

10

306301-68-8

Research Use Only

99.14

C25H18N4O2

406.44

SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 microM for ST-hSK. SKI-I also inhibits hERK2 (IC50=11 microM). SKI-I induces apoptosis in tumor cell lines[1][2].

O=C(C1=NNC(C2=CC=C3C=CC=CC3=C2)=C1)N/N=C/C4=C5C=CC=CC5=CC=C4O

2°C to 8°C

12352200