SKLB325

MedChem Express

SKLB325 [66680-03-3]

10

66680-03-3

Research Use Only

99.23

C12H12N4O2

244.25

SKLB325 is a Jumonji domain-containing 6 ( JMJD6 ) inhibitor with a binding affinity ( K D ) value of 0.755?microM, and the IC 50 value of 0.7797?microM. SKLB325 exhibits antitumor effects on ovarian cancer in vivo and in vitro. SKLB325 induces apoptosis [1] . SKLB325 exhibits remarkable antitumor efficacy in renal cell carcinoma (RCC) [2] .

OC1=NC(N/N=C/C2=CC=CC=C2O)=NC(C)=C1

-20°C,2°C to 8°C

12352200