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Chemical Structure
Chemical Structure
Chemical Structure

Skyrin [602-06-2]

Research Use Only
AG-CN2-0001
AdipoGen Life Sciences
CAS Number602-06-2
Product group Chemicals
Estimated Purity>97%
Molecular Weight538.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Skyrin
  • Delivery Days Customer
    10
  • CAS Number
    602-06-2
  • Certification
    Research Use Only
  • Estimated Purity
    >97%
  • Molecular Formula
    C30H18O10
  • Molecular Weight
    538.5
  • Scientific Description
    Chemical. CAS: 602-06-2. Formula: C30H18O10. MW: 538.5. Non-peptidic anti-diabetic agent. Receptor-selective glucagon antagonist. Free radical species ( OH, R ) and singlet oxygen (1O2) scavenger. Mycotoxin. Cytotoxic. Antioxidant. Inhibitor of botulinum neurotoxin serotype A (BoNTA). Anti-MRSA compound. Antibiotic. - Non-peptidic anti-diabetic agent [1]. Receptor-selective glucagon antagonist [1]. Free radical species ( OH, R ) and singlet oxygen (1O2) scavenger [2]. Mycotoxin [3, 4]. Cytotoxic [3, 4]. Antioxidant [2]. Inhibitor of botulinum neurotoxin serotype A (BoNTA) [5]. Anti-MRSA compound [6]. Antibiotic [7].
  • SMILES
    CC1=CC2=C(C(O)=C1)C(=O)C1=C(C2=O)C(=C(O)C=C1O)C1=C(O)C=C(O)C2=C1C(=O)C1=C(C(O)=CC(C)=C1)C2=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes: J.C. Parker, et al.; Diabetes 49, 2079 (2000)
  • Antioxidant and scavenging activity of skyrin on free radical and some reactive oxygen species: F. Vargas, et al.; Avances en Quimica 3, 7 (2008)
  • The bioactive metabolites of the mangrove endophytic fungus Talaromyces sp. ZH-154 isolated from Kandelia candel (L.) Druce: F. Liu, et al.; Planta Med. 76, 185 (2010)
  • A comparative study on cytotoxicities and biochemical properties of anthraquinone mycotoxins emodin and skyrin from Penicillium islandicum Sopp: K. Kawai, et al.; Toxicol. Lett. 20, 155 (1984)
  • Fungal bis-naphthopyrones as inhibitors of Botulinum neurotoxin serotype A: J. H. Cardellina II, e. Al.; ACS Med. Chem. Lett. 3, 387 (2012)
  • Atropisomeric dihydroanthracenones as inhibitors of multiresistant Straphylococcus aureus: R. Bara, et al.; J. Med. Chem. 56, 3257 (2013)
  • Antibiotically active metabolites from Talaromyces wortmannii, an endophyte of Aloe vera: R. Bara, et al.; J. Antibiot. 66, 491 (2013)