SLC26A3-IN-1 [307552-53-0]
HY-149802
CAS Number307552-53-0
Product group Chemicals
Molecular Weight358.39
Overview
- SupplierMedChem Express
- Product NameSLC26A3-IN-1 [307552-53-0]
- Delivery Days Customer10
- CAS Number307552-53-0
- CertificationResearch Use Only
- Molecular FormulaC23H18O4
- Molecular Weight358.39
- Scientific DescriptionSLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea[1].
- SMILESO=C(C1=C(C2=CC=CC=C2)OC3=C1C=C(OCC4=C(C)C=CC=C4)C=C3)O
- UNSPSC12131703