SLC26A3-IN-2 [950348-60-4]

MedChem Express

SLC26A3-IN-2 [950348-60-4]

10

950348-60-4

Research Use Only

99.88

C19H13ClN2O2S

368.84

SLC26A3-IN-2 is an orally active inhibitor of anion exchanger protein SLC26A3 (IC50=360 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea[1].

O=C1C=C(N=C2SC=C(N12)C3=CC=CC=C3)COC4=C(C=CC=C4)Cl

-20°C

12131703