SLC46A1 antibody, N-term

GeneTex

SLC46A1 antibody, N-term

9

WB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.5-1 mg/ml

Unconjugated

SLC46A1

solute carrier family 46 member 1

G21; HCP1; heme carrier protein 1; PCFT; proton-coupled folate transporter; solute carrier family 46 (folate transporter), member 1

Rabbit

IgG

Proton-coupled folate transporter

This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]

Human

-20°C or -80°C,2°C to 8°C

12352203