Immunohistochemistry of paraffin-embedded Human brain using SLC7A11 Polyclonal Antibody at dilution of 1/35
SLC7A11 Polyclonal Antibody
E-AB-17625
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSLC7A11 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
- UNSPSC12352203