SLP7111228 hydrochloride

Biorbyt

SLP7111228 hydrochloride

10

1449768-48-2

Research Use Only

98.00%

C22H34ClN5O

420

SLP7111228 is a potent, selective SPHK1 inhibitor with Ki values of 0.048 microM for SPHK1 and > 10 microM for SPH2K, showing a concentration-dependent reduction of sphingosine-1-phosphate (S1P) in U937 cells without affecting sphingosine levels. In vivo, it dose-dependently lowers S1P blood levels in rats.

Cl.CCCCCCCCc1ccc(cc1)-c1noc(C[C@@H]2CCCN2C(N)=N)n1

-20°C

12352200