SLU-10482

Biorbyt

SLU-10482

10

Research Use Only

98.00%

C18H16F4N6O

408.35

SLU-10482, an antiparasitic agent, effectively reduces C. parvum parasitic load in HCT-8 cells with an EC50 value of 0.07 microM. It exhibits lower affinity for human ether-a-go-go (hERG; Kd = 43 microM) compared to its counterpart, SLU-2633. When administered in vivo at dosages of 5 and 15 mg/kg twice daily, SLU-10482 significantly decreases fecal oocyst counts in mice infected with C. parvum.

FC(F)(F)C1=C(F)C=CC(CC(N2CCN(C3=NN4C(C=C3)=NN=C4)CC2)=O)=C1

-20°C

12352200