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SM1-71 [2088179-99-9]

Research Use Only
T36680
TargetMol Chemicals
CAS Number2088179-99-9
DownloadMSDS
Product group Chemicals
Molecular Weight463.96
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SM1-71 [2088179-99-9]
  • Delivery Days Customer
    10
  • CAS Number
    2088179-99-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    SM1-71
  • Molecular Formula
    C24H26ClN7O
  • Molecular Weight
    463.96
  • Scientific Description
    SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2.SM1-71 can be used as a kinase probe with anticancer activity and inhibits the proliferation of various cancer cell lines.
  • Shelf life instruction
    3 years
  • SMILES
    CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Nc3ccccc3NC(=O)C=C)n2)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Rao S, et, al. Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chem Biol. 2019 Jun 20; 26(6): 818-829.e9.
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