Immunofluorescence analysis of A549 cells using SMARCA4 Polyclonal Antibody
Immunofluorescence analysis of A549 cells using SMARCA4 Polyclonal Antibody
SMARCA4 Polyclonal Antibody
E-AB-60619
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSMARCA4 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203