Bio-Connect

SMDF (N) Antibody, Rabbit Polyclonal

ORB67017
Biorbyt
TargetNRG1
Product group Antibodies
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    SMDF antibody
  • Delivery Days Customer
    16
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Gene ID3084
  • Target name
    NRG1
  • Target description
    neuregulin 1
  • Target synonyms
    acetylcholine receptor-inducing activity; ARIA; GGF; GGF2; glial growth factor 2; heregulin, alpha (45kD, ERBB2 p185-activator); HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; neu differentiation factor; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; SMDF
  • Protein IDQ02297
  • Protein Name
    Pro-neuregulin-1, membrane-bound isoform
  • Scientific Description
    Rabbit polyclonal to SMDF.The neuregulin (also known as heregulin) cytokine family is comprised of four genes that encode anumber of secreted or membrane-bound isoforms. All family members share an EGF-like domain thatinteracts with the ErbB family of tyrosine kinase receptors. The NRG1 gene is the most pleiotropic,encoding more than 14 soluble or transmembrane proteins. NRG1 isoforms can be classified into typeI (neu differentiation factor, NDF; heregulin, HRG; acetylcholine receptor inducing activity, ARIA), typeII (glial growth factor, GGF) and type III (sensory and motor neuron-derived factor, SMDF) isoforms.These isoforms are tissue-specifically expressed and differ significantly in their structures, and theyplay important roles during development of both the nervous system and the heart. Dysregulation ofNRG1 has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203