Western blot analysis of extracts from HeLa cells, Jurkat cells, 293 cells and HUVEC cells, using SMG7 antibody.
Western blot analysis of extracts from HeLa cells, Jurkat cells, 293 cells and HUVEC cells, using SMG7 antibody.
SMG7 Antibody
CSB-PA226815
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetSMG7
Overview
- SupplierCusabio
- Product NameSMG7 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9887
- Target nameSMG7
- Target descriptionSMG7 nonsense mediated mRNA decay factor
- Target synonymsbreast cancer-associated antigen SGA-56M; C1orf16; EST1 telomerase component homolog C; EST1C; EST1-like protein C; ever shorter telomeres 1C; protein SMG7; SGA56M; smg-7 homolog, nonsense mediated mRNA decay factor
- HostRabbit
- IsotypeIgG
- Protein IDQ92540
- Protein NameProtein SMG7
- Scientific DescriptionPlays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Ohnishi T., Mol. Cell 12:1187-1200(2003). Nagase T., DNA Res. 3:321-329(1996). Nakajima D., DNA Res. 9:99-106(2002).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203