The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA290049(SMG8 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA290049(SMG8 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200)
SMG8 Antibody
CSB-PA290049
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetSMG8
Overview
- SupplierCusabio
- Product NameSMG8 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55181
- Target nameSMG8
- Target descriptionSMG8 nonsense mediated mRNA decay factor
- Target synonymsALKUS, C17orf71, nonsense-mediated mRNA decay factor SMG8, amplified in breast cancer gene 2 protein, protein SMG8, protein smg-8 homolog, smg-8 homolog, nonsense mediated mRNA decay factor
- HostRabbit
- IsotypeIgG
- Protein IDQ8ND04
- Protein NameProtein SMG8
- Scientific DescriptionInvolved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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