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SMI-4a

HY-16576A
MedChem Express
CAS Number438190-29-5
DownloadMSDS
Product group Chemicals
Estimated Purity99.63
Molecular Weight273.23
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SMI-4a [438190-29-5]
  • Delivery Days Customer
    10
  • CAS Number
    438190-29-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.63
  • Molecular Formula
    C11H6F3NO2S
  • Molecular Weight
    273.23
  • Scientific Description
    SMI-4a (TCS-PIM-1-4a) is a poten, selective, cell-permeable and ATP-competitive Pim-1 inhibitor with an IC 50 of 24 microM and a K i of 0.6 microM. SMI-4a also inhibits Pim-2 ( IC 50 of 100 microM), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity [1] .
  • SMILES
    O=C(NC/1=O)SC1=C/C2=CC=CC(C(F)(F)F)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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