SMO-IN-3 [2376914-71-3]
HY-150567
CAS Number2376914-71-3
Product group Chemicals
Molecular Weight499.50
Overview
- SupplierMedChem Express
- Product NameSMO-IN-3 [2376914-71-3]
- Delivery Days Customer10
- CAS Number2376914-71-3
- CertificationResearch Use Only
- Molecular FormulaC27H25F4N3O2
- Molecular Weight499.50
- Scientific DescriptionSMO-IN-3 (compound 12a) is a potent smoothened (SMO) inhibitor with an IC50 value of 34.09 nM for hedgehog (Hh) signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].
- SMILESO=C(N(C)C1CCN(C(C2=CC=CC=C2NC3=CC=CC=C3)=O)CC1)C4=CC=C(F)C=C4C(F)(F)F
- UNSPSC12131703