SMUG1, Human (His-SUMO)

MedChem Express

SMUG1, Human (His-SUMO)

10

Research Use Only

SMUG1

single-strand-selective monofunctional uracil-DNA glycosylase 1

FDG, HMUDG, UNG3, single-strand selective monofunctional uracil DNA glycosylase

Single-strand selective monofunctional uracil DNA glycosylase

SMUG1 protein is a single-function DNA glycosylase that plays a crucial role in base excision DNA repair, especially the recognition and repair of uracil (U) residues, preferentially recognizing mismatches (U/G) rather than matching (U/A).Its activity extends to the excision of 5-formyluracil (fU), 5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU) in single-stranded (ssDNA) and double-stranded DNA (dsDNA).SMUG1 Protein, Human (His-SUMO) is the recombinant human-derived SMUG1 protein, expressed by E.coli , with N-His, N-SUMO labeled tag.

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