SN-011

MedChem Express

SN-011 [2249435-90-1]

10

2249435-90-1

Research Use Only

99.73

C25H19FN2O4S

462.49

SN-011 is a potent and selective mouse and human STING inhibitor, with an IC 50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease [1] .

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC3=CC=C(C(NS(=O)(C4=CC=C(C=C4)F)=O)=C3)O

-20°C,2°C to 8°C

12352200