SN003

MedChem Express

SN003

14

197801-88-0

Research Use Only

C19H25N5O2

355.43

SN003 is a reversible antagonist of corticotropin releasing factor receptor 1 (CRFR 1) (IC50 = 241 nM) that displays more than 1000-fold selectivity over CRFR 2. SN003 suppresses CRF-induced ACTH release in vitro. SN003 attenuates depressive-like behavior in rat[1][2][3].

CC1=CC(N(C(COC)CC)N=N2)=C2C(NC3=CC=C(OC)C=C3C)=N1

12352200