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SN34037 [1548116-54-6]

HY-116170
MedChem Express
CAS Number1548116-54-6
Product group Chemicals
Molecular Weight344.24
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SN34037 [1548116-54-6]
  • Delivery Days Customer
    9
  • CAS Number
    1548116-54-6
  • Certification
    Research Use Only
  • Molecular Formula
    C15H19Cl2N3O2
  • Molecular Weight
    344.24
  • Scientific Description
    SN34037 is a specific inhibitor of Aldo-keto reductase 1C3 (AKR1C3, EC 1.1.1.188) with the ability to inhibit the cytotoxic activity of PR-104A. SN34037-sensitive coumberone reduction provides a rapid and specific assay for AKR1C3 activity. SN34037 inhibits the aerobic cytotoxicity of PR-104A in TF1 erythroleukemia cells with high AKR1C3 expression, but not in Nalm6 pre-B acute lymphoblastic leukemia cells with low AKR1C3 expression[1].
  • SMILES
    O=C(N1CCN(CC1)C2=CC=C(C=C2Cl)Cl)N3CCOCC3
  • UNSPSC
    12352200

MSDS

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