SNIPER(ABL)-024 [2222355-77-1]

MedChem Express

SNIPER(ABL)-024 [2222355-77-1]

10

2222355-77-1

Research Use Only

C52H61F3N8O9S

1031.15

SNIPER(ABL)-024, conjugating GNF5 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 5microM[1].

O=C(NCCOCCOCCOCCOC1=CC(C(C2=CSC([C@H]3N(C([C@H](C4CCCCC4)NC([C@H](C)NC)=O)=O)CCC3)=N2)=O)=CC=C1)C5=CC=CC(C6=NC=NC(NC7=CC=C(OC(F)(F)F)C=C7)=C6)=C5

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