SNIPER(BRD)-1 [2095244-54-3]
HY-111875
CAS Number2095244-54-3
Product group Chemicals
Estimated Purity98.4%
Molecular Weight1056.73
Overview
- SupplierMedChem Express
- Product NameSNIPER(BRD)-1 [2095244-54-3]
- Delivery Days Customer10
- CAS Number2095244-54-3
- CertificationResearch Use Only
- Estimated Purity98.4%
- Molecular FormulaC53H66ClN9O8S2
- Molecular Weight1056.73
- Scientific DescriptionSNIPER(BRD)-1, consists of an IAP antagonist LCL-161 derivative and a BET inhibitor, (+)-JQ-1, connected by a linker. SNIPER(BRD)-1 induces the degradation of BRD4 via the ubiquitin-proteasome pathway. SNIPER(BRD)-1 also degrades cIAP1 , cIAP2 and XIAP with IC50s of 6.8 nM, 17 nM, and 49nM, respectively.
- SMILESO=C(C[C@H]1C2=NN=C(C)N2C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N1)NCCOCCOCCOCCOC5=CC(C(C6=CSC([C@H]7N(C([C@@H](NC([C@H](C)NC)=O)C8CCCCC8)=O)CCC7)=N6)=O)=CC=C5
- Storage Instruction-20°C,-80°C
- UNSPSC12352200