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SNRPB antibody

GTX101883
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetSNRPB
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Overview

  • Supplier
    GeneTex
  • Product Name
    SNRPB antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.38 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6628
  • Target name
    SNRPB
  • Target description
    small nuclear ribonucleoprotein polypeptides B and B1
  • Target synonyms
    CCMS, COD, SNRPB1, Sm-B/B', SmB/B', SmB/SmB', snRNP-B, small nuclear ribonucleoprotein-associated proteins B and B', B polypeptide of Sm protein, Sm protein B/B', sm-B/Sm-B', small nuclear ribonucleoprotein polypeptide B, small nuclear ribonucleoprotein polypeptides B and B'
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP14678
  • Protein Name
    Small nuclear ribonucleoprotein-associated proteins B and B'
  • Scientific Description
    The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B) have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • McGrail DJ, Li Y, Smith RS, et al. Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins. Cell Rep Med. 2023,4(11):101255. doi: 10.1016/j.xcrm.2023.101255
    Read this paper