SNRPN blocking peptide

GeneTex

SNRPN blocking peptide

9

Neutralisation/Blocking

Research Use Only

200 ug/ml

Unconjugated

SNRPN

small nuclear ribonucleoprotein polypeptide N

HCERN3, PWCR, RT-LI, SM-D, SMN, SNRNP-N, SNURF-SNRPN, sm-N, small nuclear ribonucleoprotein-associated protein N, SM protein N, sm protein D, tissue-specific splicing protein

The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5 untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5 UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or

-20°C

41116100

Human