SNX-5422

MedChem Express

SNX-5422 [908115-27-5]

14

908115-27-5

Research Use Only

99.11

C25H30F3N5O4

521.53

SNX-5422 (PF-04929113), a prodrug of SNX-2112, is an orally active Hsp90 inhibitor, with a K d of 41 nM, and also induces Her-2 degradation, with an IC 50 of 37?nM.

FC(F)(C1=NN(C2=CC(N[C@@H]3CC[C@H](CC3)OC(CN)=O)=C(C=C2)C(N)=O)C(CC(C)(C4)C)=C1C4=O)F

-20°C,2°C to 8°C

12352200